In recent decades the deepest and widest enmity based interaction must be looked for in relations between Iran and America. If we assume the enmity between America and the Soviet Union was the symbol of the cold war era, after the disintegration of macro ideological hostility between the two super powers the face of the present international system has to be sketched based on very hostile interaction and existential conflict between Tehran and Washington. The question has to deal with this: what is the foundation of mutual action policy based on zero sum game(victory for one comes only through the destruction of the other) between Iran and America? Comprehensive and continuous efforts to make ineffective and if possible to replace settled arrangements in the region and transformation of the quality of distribution of power in the system which gives the US the most dividend by Iran (in the context of balance of power strategy) and on the other hand, conscious and purposeful practices, simultaneously, to bring about soft disorder(to shape conditions in order to change elites in the authority to a destructive ones and to enhance the position of the domestic opposition of the system in order to cause instability)and hard disorder(establishing embargo and pushing Iran ) by the US (in the context of hegemonic strategy) are the background of the animosity between these two capitals