ملاحظات أمنیتی دیپلماسی علمی در حوزه مطالعات ژن پژوهی پیرامون ژنوم إیرانیان

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشجوی دکتری حقوق خصوصی، گروه حقوق، واحد نیشابور، دانشگاه آزاد اسلامی، نیشابور، ایران.

2 استادیار گروه حقوق، واحد شاندیز، مؤسسه آموزش عالی، شاندیز، ایران

3 استادیار گروه حقوق، واحد نیشابور، دانشگاه آزاد اسلامی نیشابور، ایران

چکیده

موضوع إرتباط همکاریهای فناورانه در حوزة پژوهشهای ژنتیک إنسان محور با مباحث مربوط به حقوق بشر (حق حیات و حق بر سلامتی) از یکسو، کارکردهای مخفی دستیابی به شناسنامه ژنتیکی شهروندان از سوی دیگر، موجب شده جنبه‌های أخلاقی، سیاسی، أمنیتی و حقوقی قراردادهای مبتنی بر ژنوم، بسیار مهمتر از جنبه پزشکی آن باشد. لذا ضرورت دارد، کشورهای در حال توسعه، با بررسی جنبه های سیاسی، أمنیتی و إجتماعی با ایجاد أبزارهای ویژة حمایتی و نظارتی، تعاملات و مراودات علمی در حوزه منابع ژنتیک إنسانی را کنترل، توسعه و حمایت کنند. یافته ها: گرچه، استفاده از ظرفیتهای دیپلماسی علمی و همکاریهای فناورانه درزمینه ژن پژوهی و نقل و إنتقال فرامرزی رده های سلولی و ژنوم إنسانی، علاوه بر إرتقاء کمی وکیفی إعتبار پژوهش، بستر مساعدی پیرامون إمکان تجزیه و تحلیل متمرکز و هماهنگ روی نمونه های سلولی و بیولوژیکی فراهم آورده؛ لیکن، إبداع شیوه های مدرن تکثیر و ویرایش ژن، همچنین کارکردهای بالقوه إطلاعات ژنتیکی مکتسب از نمونه های إنسانی، باعث بروز حساسیتهای مضاعفی از طرف أنجمنها و أرگانهای دولتی، خصوصاً درزمینه إستفاده نابجای إحتمالی از این ذخیره إطلاعاتی شده است.

کلیدواژه‌ها


عنوان مقاله [English]

Security considerations of scientific diplomacy in the field of gene research studies about the Iranian genome

نویسندگان [English]

  • zahra khosrojerdi 1
  • mohammad reza gholampour 2
  • Seyyed Mohsen Hosseini Pooya 3
1 PHD student of private law, Department of Law, Neyshabur Branch, Islamic Azad University, Neyshabor, Iran.
2 Department of Law, Shandiz Branch, Institute of Higher Education, Shandiz, Iran
3 Assistant Professor, Department of Law, Neyshabor Branch, Islamic Azad University, Neyshabor, Iran
چکیده [English]

he issue of the relationship between technological cooperation in the field of human-centered genetic research and human rights issues (right to life and right to health) on the one hand, and the hidden functions of obtaining citizens' genetic IDs on the other hand, have made the ethical, political, security, and legal aspects of genome-based contracts much more important than their medical aspects. Therefore, it is necessary for developing countries to control, develop, and support scientific interactions and exchanges in the field of human genetic resources by examining the political, security, and social aspects and creating special support and monitoring tools. Findings: However, the use scientific diplomacy capacities and technological cooperation in the field of gene research and cross-border transfer of cell lines and human genomes, in addition to quantitatively and qualitatively improving the credibility of research, has provided favorable environment for the possibility of centralized and coordinated analysis of cellular and biological samples; However, the invention of modern methods of gene replication and editing, as well as the potential functions of genetic information obtained from human samples,

Introduction

Today, mineral resources and military power are no longer regarded as the sole components of power; rather, technological advancements and international collaborations in technology have become key components of a country’s soft power. These factors serve as potent tools to project national capabilities, strength, and prestige, thus attracting the attention of policymakers.  While remarkable genetic interventions in the human genome have created an optimistic outlook for the treatment of genetic defects and the improvement of public welfare, the growing non-medical uses of genetic data, such as in employment, insurance, judicial authorities, and educational institutions have raised numerous legal, ethical, and security concerns. These concerns include the potential violation of citizens’ genetic privacy, the imposition of unjust discrimination, the unfair acquisition of intellectual property rights over genetic resources, and the development of biological weapons. Consequently, leading countries have made considerable efforts to regulate the use of biological and laboratory samples from their citizens. This emerging genetic trade, compared to other economic revolutions in history, has been accompanied by troubling ethical issues and consequences.

Theoretical Framework

Unfortunately, the lack of coordination in regulating the use of human genetic resources, relative to the rapid advancements in genetics and the increasing number of research centres in this field, creates a legal gap. This gap jeopardises human dignity and the right to life, making it challenging to address its consequences. Given that products derived from the human genome directly impact the health and dignity of individuals, they are fundamentally different from other scientific, industrial, and commercial creations. The predictive nature of the human genome, regarding the hereditary and clinical characteristics of individuals, highlights the need for precautionary measures and legal guarantees such as legislative, judicial, and criminal policies, alongside security and political strategies to protect the confidentiality of these data and the conditions governing biobanks. This ensures that the findings derived from genetic data do not lead to genetic discrimination or the restriction of individuals' human, customary, and legal rights in areas like employment, insurance, or biological misuse against national security.  Genetic data from ethnic groups and nationalities, as well as innovations from genetic research, are considered part of the economic assets of individuals and the scientific secrets of nations.  Given these concerns, and emphasising the need for more thorough reflection by researchers and policymakers, this paper seeks to address the key question: What specific actions should Iran take at the international level to protect and legally safeguard the biological data of its citizens or ethnic groups, while strengthening the infrastructure of its genomic industry?

Methodology

A review of existing literature on national security reveals that most studies have focused on national security from a military perspective, with some addressing it from economic or other angles. However, studies on national security from the perspective of modern technologies, particularly human genetic biotechnology, remain scarce. This research offers a novel contribution in this regard. The findings are based on a qualitative, exploratory study. Data were gathered from library resources, newspapers, reputable journals, and online databases. In addition to the purposeful use of library and internet sources, consultations with experts in related fields have enriched the study.

Results & Discussion

A key pillar of societal strength is "health" and "national security," both of which are targeted by adversaries through lifestyle choices. In recent years, biological threats have led to a redefinition of "security" as strengthening defences against biological risks and preparing for biological incidents. Iran’s defence policy, guided by verse 60 of Surah Al-Anfal:" وَأَعِدُّوا لَهُم مَّا اسْتَطَعْتُم مِّن قُوَّةٍ "And prepare against them whatever you are able of power..." emphasises enhancing biotechnology defence capabilities for deterrence, safeguarding the country, and managing crises caused by various threats. This is achieved through the development and implementation of a biological defence programme, which aims to prevent terrorists from accessing biological agents, equipment, and the technical knowledge required to develop biological weapons.

Conclusions & Suggestions

Iran's position regarding international technological cooperation in genomic research, including the exchange of citizens’ genetic data, considers the importance of public order, prioritises the security of the Muslim community, and seeks to prevent foreign domination due to the potential for espionage. Such collaborations may aim to access sensitive information and uncover weaknesses that could harm national security. To mitigate these risks, Iran aims to strengthen domestic research infrastructure, including properly equipping laboratories, providing financial support for knowledge-based companies, and localising science and technology. Nevertheless, when it comes to beneficial genetic research, given the pivotal role of human biotechnology in strengthening scientific, economic, and defence capabilities, and in cases where domestic laboratory facilities are lacking, tissue samples may need to be sent abroad. In such cases, the selection of partner countries should be based on political, social, and cultural factors, considering the country’s specific conditions to ensure the benefit of the studied community..
 

کلیدواژه‌ها [English]

  • Scientific Diplomacy
  • Genetic Research and Genome Transfer Contracts
  • Human Subjects
  • Passive Defense
Adam, D. (2016). Could you make a genetically targeted weapon? The Guardian, archived from the original on 19 April 2016. https://en.wikipedia.org/wiki/Ethnic_bioweapon.
Ahmadinejad, H., & Qorbani Sheikhneshin, A. (2022).  Identify the Covid-19 crisis based on the crisis cube and the explanation of its effects on the international. World Politics Quarterly, Volume 10, Issue 4. 135-171.
Doi: 10.22124/wp.2022.5519. [In Persion].
Ain Allahi, B. (2023). The genetic information of Iranians should not be taken out of the country, (news code: 2797438), Tasnim news agency base, November 1, 2023.
Amjadi, M. H., Mehrabi Boshrabadi, H. & Jahanarai N. (2020). Ranking of the country's provinces from the perspective of knowledge-based economy indicators, Strategic Scientific Quarterly, Volume 94, Issue 29, 187-193. [In Persion].
Aparat Film, Fan Vox's America Dereligious Project. (2018 April 20). [Video file]. Available at: https://www.aparat.com/v/nYMI6. [In Persion].
Arnaldi, S. (2023). Science diplomacy. Foundations and practice. Italy: EUT Editions University of Trieste.  Available at: https://en.wikipedia.org/wiki/Ethnic_bioweapon.
Bojnordi, M. (2022). Jurisprudence Rules. First volume, Tehran: Oruj Institute. [In Persian]
Cultural Headquarters of the Secretariat of the Supreme Council of Cultural Revolution. (2020), Analysis of biological wars history / natural or artificial nature of corona virus. [Report]. Available at: Available at: https://sccr.ir/files/26905.pdf. [In Persion].
Dayalu A. (2002). Harvard Project in China Violates Farmers' Rights. People's Daily Online. https://chinaproject.harvard.edu/search/site/Dayalu%2C%20Archana=%20.&solrsort
 Dunn C. Mc. & Chadwick G. (2004). Protecting study volunteers in research, 3rd Edition, Boston: Center Watch press.
Greenberg, D. S. (2003). Science, Money, and Politics: Political Triumph and Ethical Erosion. 1th Edition, Chicago, Illinois: University of Chicago Press.
Hosseini Khamenei A. (2019). Graduation ceremony of students of Imam Hussein University (AS), in Imam Hussein University (Speech), 2019 October 13. [In Persion].
Iranian diplomacy news base. (2023 December 11). Relations between Iran and Cuba are a win-win relationship (news code: 2023547). http://www.irdiplomacy.ir/fa/news/2023547. [In Persion].
Jabal Ameli M., Yazdani Zazrani M.R., Guderzi M. (2024). Pathology of policies related to genetically modified crops in the Islamic Republic of Iran. Strategic Studies Quarterly, Volume 27, Issue 2. 43-64. [In Persion].
Jafari A. A. & Ghorbi M.J. (2018). Sources of soft power of the Islamic Republic of Iran; A quantitative study of the general policies of science and technology, Research. Journal of the Islamic Revolution, Volume 8, Issue 27. 151-175. [In Persion].
Jafari Nia A., Akhbari M., Moradian M. (2019) Analysis of military power indicators of political-geographical units in the field of international system. Quarterly of New Approaches in Human Geography, Volume 11, Issue 3. 445-465. [In Persion].
Jalali Gh. (2018 April 18). Corona is a biological and economic war (news code: 4903087). Mehr News Agency. Available at: Mehrnews.com/xRH72. [In Persion].
Kevles, D.J. (1995). In the name of eugenics: Genetics and the uses of human heredity. Cambridge, MA: Harvard University Press.
Larijani B. & Zahedi F. (2006). A comment on ethical committees in research in Iran and the world, Iranian Journal of Diabetes and Fat, Volume 5, Issue 5. P.281-297. [In Persion].
Madani H. (2022 February 24). Iran's first rank in the production of biotechnology products in the Asian continent / foreign exchange savings of 8.1 billion dollars (news code: 245510). Fars news agency base. To the address: http://fna.ir/6kugi. [In Persian].
Marginson S. (2010). Higher education in the global knowledge economy. Journal ProcediaـSocial and Behavioral Sciences, Publisher: Elsevier scientific base, Volume 2, Issue 5. PP. 6962-6980. DOI:10.1016/j.sbspro. 2010.05.049.
Mirkooshesh A. (2018). Scientific and technological diplomacy and national power, Journal of Politics and International Relations, Volume 2, Issue 1. PP: 129-146. https://doi.org/10.22080/jpir.2018.2053 [In Persion].
Mousavi Hamdani M.B. (2015). Translation of Tafsir al-Mizan by Allameh Tabatabai. Volume 9, Qom: Islamic Publications Office affiliated with the Qom Seminary Teachers' Society. [In Persion].
Naini, A.M. (2007). Soft threat, dimensions and characteristics. Journal of Psychological Operations, Volume 4, Issue 16. P.134-155. [In Persion].
Novbahar R. (2004). International Journal of Human Genetic Data; Its concerns, approaches and compatibility with Islamic views. Comparative Law Quarterly, Volume 46, Issue 7. PP: 61-98. [In Persion].
Norouzian M. (2006). Standing Committee for Scientific and Technological Cooperation of COMSTECH. Islamic Conference Organization (COMSTECH), Rehiyaft Quarterly, Volume 15, Issue 35. PP: 34-37. [In Persion].
Qadiri Bahramabadi, R. (2017). Conflict between right and expediency (with an emphasis on terrorist crimes), Judicial Law Journal, Volume 81, Issue 98. PP: 147-173. [In Persion].
Qanei M. (2016) Mesgarpur B. Parsapour A. Saadat, H. Bamdadi F. Mahmoud Rabati, A. Karamati A. Ethical Executive Management in Medical Science Research, Iranian Journal of Medical Ethics and History, Volume 1, Issue 1. PP: 1-16. [In Persion].
Qasimpour. Y. (2024 April 13). Research theory of advanced defense research projects: an introduction to DARPA (news code: 2025507). Iran diplomacy news base report.
Available at: http://www.irdiplomacy.ir/fa/news/2025507. [In Persion].
Rajabi M. (2012). A review of international sanctions and human rights standards (with an emphasis on multilateral sanctions against Iran), Islamic Human Rights Studies Quarterly, 24 (1) 155-158. [In Persion].
Sadeghi, S. (2020). Comparative study of biological crimes in international law and Iran. Master's thesis. Law Group, Faculty of Law and Theology, Shahid Ashraf Isfahani University. [In Persian]
Salehi Imran A. & Karamkhani Z. (2013). Investigating Iran's contribution to international higher education compared to other countries. Proceedings of the 6th International Conference of Iran Higher Education Association, Ferdowsi University of Mashhad: Greater Iran Education Association. [In Persion].
Samii, S. (2017 July 3). Details of notification of instructions for issuing a license to send laboratory samples abroad” (news code: 295735). Government information base. https://dolat.ir/detail/295735. [In Persion].
Shawardi M. (2018). Technology phobia and ways to deal with it, Rushd Tehsil Quarterly, Volume 14, Issue 55. PP: 76-82. [In Persion].
Sputnik. (2020). Iranian authorities announced the secret activity of American biological laboratories around the country (news code: 706645), Sputnik news base. Available at: https://spnfa.ir/20201025/7066458. [In Persion].
Tajeh Miri A., Azimi M.N., Amiri Moghadam B., et al. (2002). The necessity of setting up diagnostic knowledge-based laboratories for the sustainable development of the western region of the country, international conference on knowledge-based production and job creation with the focus of urban mobilization, Tehran: Zamin Sazeh Sadra Company, 1-17. [In Persion].
Tasnim News Agency. (2020 March 13). International Group. Persistent doubts about the origin of Corona; who believes that Corona is the result of American biological warfare? (News code: 2222657). Tasnim News Agency. Available at: https://tn.ai/2222657. [In Persion].
Vezin Karimian, M. (2011). Development of biotechnology, from the perspective of vision document 1404 and general policies of the system (legal approach). Journal of Medical Law, Volume 4, Issue 12. PP:13-24. [In Persion].
Waziri I. (2021). Sabouri A.A. International Scientific Interactions: Drivers of Science and Technology Diplomacy. Nesha Alam Journal, 12 (1), 15-16. [In Persion].
Wired New. (1998 November 16) .Israel's Ethnic Weapon? Archived from the original on 2002 April 28. https://en.wikipedia.org/wiki/Ethnic_bioweapon.
Zulfiqarzadeh, M.M., Hajri M. Eftekhari H. (2016). The role of science and technology diplomacy in improving the challenges of knowledge-based companies, Growth and Technology Quarterly, Volume 48, Issue 12.  PP: 1-10. [In Persion].
Zumla A. Anthony C. (2002). Ethical Issues in Research in Developing Countries. JRSM (Journal of Royal Society of Medicine), London: Nuffield Council on Bioethics, Volume 95, Issue 6. PP: 275–276. DOI:10.1016/j.sbspro. 2010.05.049.